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Phenotypic Profiling of Tigecycline-resistant Klebsiella pneumoniae Strains Induced In vitro.

Current microbiology - 13 Dec 2024

Wei Zilan, Xu Jie, Wu Jiahui, Wang Youliang, Chen Shuiping

Abstract excerpt

Tigecycline is one of the last-resort treatment options for infections caused by carbapenem-resistant Klebsiella pneumoniae (KP). Unfortunately, tigecycline resistance is increasingly reported and causes an unprecedented public health crisis worldwide. Although studies on tigecycline resistance are expanding, the underlying mechanisms are not fully understood. The goal of this study is to investigate...

Topics

Tigecycline
Klebsiella pneumoniae
Anti-Bacterial Agents
Microbial Sensitivity Tests
Bacterial Proteins
Drug Resistance, Bacterial
Phenotype
Biofilms
Gene Expression Regulation, Bacterial

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PMID: 39671135
DOI: 10.1007/s00284-024-04018-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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