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Computational analysis of the functional impact of MHC-II-expressing triple-negative breast cancer

27 Nov 2024

Abstract excerpt

The tumor microenvironment (TME) plays a crucial role in tumor progression and immunoregulation. Major histocompatibility complex class II (MHC-II) is essential for immune surveillance within the TME. While MHC-II genes are typically expressed by professional antigen-presenting cells, they are also expressed in tumor cells, potentially facilitating antitumor immune responses. To understand the role of...

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PMID: 39664386
DOI: 10.3389/fimmu.2024.1497251

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