Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Melanoma Tumor Mutational Burden and Indoor Tanning Exposure.

JAMA dermatology - 1 Feb 2025

Hanrahan Grace B, Giobbie-Hurder Anita, Allais Blair, Vogelzang Jayne, Fay Christopher, Tsibris Hillary C

Abstract excerpt

Importance: UV-induced mutagenesis leads to a higher tumor mutational burden (TMB) in cutaneous melanoma relative to other cancer types. TMB is an important prognostic marker in advanced melanoma; higher TMB is associated with greater clinical response to immune checkpoint inhibition and improved survival. Objective: To evaluate the association between cutaneous melanoma TMB and indoor tanning exposure, as well...

Read the complete abstract on PubMed

Topics

Humans
Melanoma
Male
Skin Neoplasms
Female
Middle Aged
Retrospective Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Sunbathing

Aged

Ultraviolet Rays

Mutation

Biomarkers, Tumor

High-Throughput Nucleotide Sequencing

Source

Open in PubMed Open full text

Identifiers

PMID: 39661348
DOI: 10.1001/jamadermatol.2024.4819
PMCID: PMC11840639

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 21 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Melanoma Tumor Mutational Burden and Indoor Tanning Exposure.PMID 39661348Read ↗

Molecular effects of indoor tanning.Semantic proximity Read ↗

Molecular effects of indoor tanningSemantic proximity Read ↗

Impact of Sun Exposure and Tanning Patterns on Next-Generation Sequencing Mutations in Melanoma.Semantic proximity Read ↗

Emerging trends in the epidemiology of melanoma.Semantic proximity Read ↗

Cohort studies on melanoma and keratinocyte skin cancer: a systematic reviewSemantic proximity Read ↗

Cutaneous and acral melanoma cross-OMICs reveals prognostic cancer drivers associated with pathobiology and ultraviolet exposureSemantic proximity Read ↗

Cutaneous and acral melanoma cross-OMICs reveals prognostic cancer drivers associated with pathobiology and ultraviolet exposure.Semantic proximity Read ↗

Phenotypic and genotypic risk factors for invasive melanoma by sex and body site.Semantic proximity Read ↗

DNA repair variants, indoor tanning, and risk of melanoma.Semantic proximity Read ↗

Keratinocyte Carcinomas: Current Concepts and Future Research PrioritiesSemantic proximity Read ↗

Melanoma Epidemiology and Prevention.Semantic proximity Read ↗

Melanoma etiology: where are we?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.