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Article

Can a Hybrid Line Break a Selection Limit on Behavioral Evolution in Mice?

Behavior genetics - 1 Jan 2025

Hiramatsu Layla, Careau Vincent, Garland Theodore

Abstract excerpt

Artificial selection yielded four replicate high runner (HR) lines of mice that reached apparent selection limits (~ threefold increase in wheel revolutions per day vs. four control lines), despite maintenance of additive genetic variance. After 68 generations, we used animal models to test for changes in additive-genetic variances and covariance of the two measured components (average speed and duration) of...

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Identifiers

PMID: 39636486
DOI: 10.1007/s10519-024-10209-7
PMCID: PMC11790750

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