Article
Antibiotic resistance genotype, phenotype, and clinical outcomes in patients with Gram-negative infections at Rabin Medical Center in Israel.
Microbiology spectrum - 7 Jan 2025
Koch Rachelle E, Barth Jackson, Clark Andrew E, Desai Dhara, Kim Jiwoong, Pybus Christine A, Zhan Xiaowei, Leibovici Leonard, Yahav Dafna, Greenberg David E
Abstract excerpt
Antibiotic resistance is a major cause of morbidity and mortality. However, a better understanding of the relationship between bacterial genetic markers, phenotypic resistance, and clinical outcomes is needed. We performed whole-genome sequencing on five medically important pathogens (Acinetobacter baumannii, Enterobacter cloacae, Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa) to investigate...
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