Article
Allele C of rs6068816 in the CYP24A1 Gene is Associated with Increased Risk of Hyperuricemia in the Chinese Population: A Case-Control Study.
Discovery medicine - 1 Nov 2024
Shangguan Jiahong, Zhang Wenjing, Zhu Xiaodan, Zheng Yingying, Xue Rui, Xiao Lili, Liu Gangqiong
Abstract excerpt
BACKGROUND: Vitamin D (1,25-(OH)2D) has been reported to be associated with hyperuricemia in many epidemiologic reports. CYP24A1 is a rate-limiting enzyme involved in vitamin D metabolism. The aim of this study was to investigate the association between the rs6068816 polymorphism in the CYP24A1 gene and hyperuricemia. METHODS: 130 patients with hyperuricemia from the First Affiliated Hospital of Zhengzhou...
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