Article
Prevalence, genetic variants, and clinical implications of hypocholesterolemia in children.
Atherosclerosis - 1 Jan 2025
Groselj Urh, Kafol Jan, Molk Neza, Sedej Katarina, Mlinaric Matej, Sikonja Jaka, Sustar Ursa, Kern Barbara Cugalj, Kovac Jernej, Battelino Tadej, Debeljak Marusa
Abstract excerpt
BACKGROUND AND AIMS: In contrast to extensively studied hypercholesterolemia, knowledge of hypocholesterolemia is limited. This study aims to assess the prevalence, clinical characteristics, and genetics of children and adolescents with hypocholesterolemia. METHODS: This national prospective cross-sectional cohort study was part of Slovenia's universal opt-out cholesterol screening program. The first part...
Topics
- Humans
- Male
- Female
- Child
- Prevalence
- Cross-Sectional Studies
- Prospective Studies
- Child, Preschool
- Adolescent
- Slovenia
- Cholesterol
- Phenotype
- Genetic Predisposition to Disease
- Hypercholesterolemia