Article
Tailoring cell therapies for diabetic metabolic phenotypes: a comparative study on the efficacy of various umbilical cord-derived cell regimens.
Stem cells translational medicine - 11 Feb 2025
Wang Lingshu, Wang Liming, He Falian, Song Jia, Qiao Jingting, Qin Jun, Chen Li, Hou Xinguo
Abstract excerpt
Given the high heterogeneity of type 2 diabetes mellitus (T2DM), it is imperative to develop personalized stem cell infusion regimen for targeted metabolic phenotype in order to ensure optimal therapeutic efficacy. In this study, we conducted a comparative analysis of 4 infusion regimens involving single and repeated infusions of human umbilical cord Wharton's jelly-derived MSCs (hucMSCs), single infusions of...
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