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Article

Targeted multiplex proteomics for the development and validation of biomarkers in primary aldosteronism subtyping

18 Nov 2024

Abstract excerpt

OBJECTIVE: Primary aldosteronism (PA), a significant cause of secondary hypertension affecting ∼10% of patients with severe hypertension, exacerbates cardiovascular, and cerebrovascular complications even after blood pressure control. PA is categorized into two main subtypes: unilateral aldosterone-producing adenomas (APA) and bilateral hyperaldosteronism (BHA), each requiring distinct treatment approaches....

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PMID: 39556467
DOI: 10.1093/ejendo/lvae148

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