Successful colonization of the testicular germinal epithelium by bone marrow stem cells producing spermatozoa of donor genotype is rare.

Abstract excerpt

BACKGROUND: It is not known whether bone marrow stem cells when injected intravenously for a bone marrow transplant colonize the human testicular epithelium. No previous studies of sperm genotype after bone marrow transplantation are reported. OBJECTIVES: To differentiate host from donor genotype in spermatozoa of men who have undergone successful bone marrow transplants. MATERIALS AND METHODS: Triplet DNA...

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