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Article

Causality between autoimmune diseases and schizophrenia: a bidirectional Mendelian randomization study.

BMC psychiatry - 16 Nov 2024

Duan Lincheng, Li Shiyin, Chen Dongnan, Shi Yue, Zhou Xianhua, Feng Yue

Abstract excerpt

BACKGROUND: Observational studies have shown a link between autoimmune diseases and schizophrenia, with conflicting conclusions. Due to the existence of confounding factors, the causal link between autoimmune diseases and schizophrenia is still unknown. METHOD: We conducted a comprehensive Mendelian randomization (MR) analysis of schizophrenia and ten common autoimmune diseases in individuals of European descent...

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Identifiers

PMID: 39550571
DOI: 10.1186/s12888-024-06287-w
PMCID: PMC11568594

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