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Article

Exploring causal associations between autoimmune diseases and hearing loss: a mendelian randomization study.

Brazilian journal of otorhinolaryngology - 1 Jan 2026

Huang Yutong, Gao Shengli, Luo Renzhong

Abstract excerpt

OBJECTIVE: The causal relationship between Autoimmune Diseases (ADs) and Hearing Loss (HL) remains unclear. This study investigates whether genetic predispositions associated with ADs contribute to HL risk. METHODS: Mendelian Randomization (MR) analysis was conducted to explore the causal effects of ADs on HL. SNPs from Genome-Wide Association Studies (GWAS) were used as instrumental variables for ADs, including...

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Topics

Humans
Mendelian Randomization Analysis
Autoimmune Diseases
Polymorphism, Single Nucleotide
Genetic Predisposition to Disease
Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Hearing Loss

Risk Factors

Source

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Identifiers

PMID: 42208083
DOI: 10.1016/j.bjorl.2026.101837
PMCID: PMC13240669

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