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Mitochondrial ATP synthesis is essential for efficient gametogenesis in Plasmodium falciparum

16 Nov 2024

Abstract excerpt

Plasmodium male and female gametocytes are the gatekeepers of human-to-mosquito transmission, therefore essential for propagation of malaria within a population. Whilst dormant in humans, their divergent roles during transmission become apparent soon after mosquito feeding with a rapid transformation into gametes - males forming eight motile sperm-like cells aiming to fertilise a single female gamete. Little is...

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PMID: 39550509
DOI: 10.1038/s42003-024-07240-z

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