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Modeling extrahepatic hepatitis E virus infection in induced human primary neurons

15 Nov 2024

Abstract excerpt

Hepatitis E virus (HEV) infections are one of the most common causes of acute viral hepatitis, annually causing over 3 million symptomatic cases and 70,000 deaths worldwide. Historically, HEV was described as a hepatotropic virus, but has recently been associated with various extrahepatic manifestations including neurological disorders such as Guillain-Barré syndrome and neuralgic amyotrophy. However, the...

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PMID: 39546567
DOI: 10.1073/pnas.2411434121

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