Article
Metabolic Phenotype and Risk of Obesity-Related Cancers in the Women's Health Initiative.
Cancer prevention research (Philadelphia, Pa.) - 3 Feb 2025
Karra Prasoona, Hardikar Sheetal, Winn Maci, Anderson Garnet L, Haaland Benjamin, Shadyab Aladdin H, Neuhouser Marian L, Seguin-Fowler Rebecca A, Thomson Cynthia A, Coday Mace, Wactawski-Wende Jean, Stefanick Marcia L, Zhang Xiaochen, Cheng Ting-Yuan David, Karanth Shama, Sun Yangbo, Saquib Nazmus, Pichardo Margaret S, Jung Su Yon, Tabung Fred K, Summers Scott A, Holland William L, Jalili Thunder, Gunter Marc J, Playdon Mary C
Abstract excerpt
Body mass index (BMI) may misclassify obesity-related cancer (ORC) risk, as metabolic dysfunction can occur across BMI levels. We hypothesized that metabolic dysfunction at any BMI increases ORC risk compared with normal BMI without metabolic dysfunction. Postmenopausal women (n = 20,593) in the Women's Health Initiative with baseline metabolic dysfunction biomarkers [blood pressure, fasting triglycerides,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.