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Genetic diversity of Plasmodium vivax population in northeast Myanmar assessed by amplicon sequencing of PvMSP1 and PvMSP3α.

Acta tropica - 1 Dec 2024

Wei Xiaoyuan, Malla Pallavi, Wang Zenglei, Yang Zhaoqing, Cao Yaming, Wang Chengqi, Cui Liwang

Abstract excerpt

This study aimed to assess the baseline genetic diversity of the Plasmodium vivax population in an endemic area of northeast Myanmar at the onset of the malaria elimination campaign in the Greater Mekong Subregion. We genotyped 125 P vivax clinical samples at two merozoite surface protein loci, PvMSP1 and PvMSP3α, by amplicon deep sequencing. Our study revealed that the parasite population in this region was...

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PMID: 39536889
DOI: 10.1016/j.actatropica.2024.107461

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