Metagenomic profiling of nasopharyngeal samples from adults with acute respiratory infection

Abstract excerpt

Diagnosis of acute respiratory infections (ARIs) is challenging due to the broad diversity of potential microbial causes. We used metagenomic next-generation sequencing (mNGS) to analyze the nasopharyngeal virome of ARI patients, who had undergone testing with a clinical multiplex PCR panel (Amplisens ARVI-screen-FRT). We collected nasopharyngeal swabs from 49 outpatient adults, 32 of whom had ARI symptoms and...

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• Bacteriophages and microbial interactions
• Microbial infections and disease research
• Respiratory viral infections research