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Article

Fitness consequences of structural variation inferred from a House Finch pangenome.

Proceedings of the National Academy of Sciences of the United States of America - 19 Nov 2024

Fang Bohao, Edwards Scott V

Abstract excerpt

Genomic structural variants (SVs) play a crucial role in adaptive evolution, yet their average fitness effects and characterization with pangenome tools are understudied in wild animal populations. We constructed a pangenome for House Finches (Haemorhous mexicanus), a model for studies of host-pathogen coevolution, using long-read sequence data on 16 individuals (32 de novo-assembled haplotypes) and one outgroup....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39531493
DOI: 10.1073/pnas.2409943121
PMCID: PMC11588099

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