Article
Genotype and corticosteroid treatment are distinctively associated with gray matter characteristics in patients with Duchenne muscular dystrophy.
Neuromuscular disorders : NMD - 1 Dec 2024
Geuens Sam, Van Dessel Jeroen, Kan Hermien E, Govaarts Rosanne, Niks Erik H, Goemans Nathalie, Lemiere Jurgen, Doorenweerd Nathalie, De Waele Liesbeth
Abstract excerpt
This study investigated if structural variation in specific gray matter areas is associated with corticosteroid treatment or genotype, and if cerebral morphological variations are related to neuropsychological and behavioral outcomes. The CAT12 toolbox in SPM was used for MRI segmentations, assessing subcortical structures, cortical thickness, gyrification, and sulci depths for DMD patients (n = 40; 9-18 years)...
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