Article
Precision phenotyping for curating research cohorts of patients with unexplained post-acute sequelae of COVID-19.
Med (New York, N.Y.) - 14 Mar 2025
Azhir Alaleh, Hügel Jonas, Tian Jiazi, Cheng Jingya, Bassett Ingrid V, Bell Douglas S, Bernstam Elmer V, Farhat Maha R, Henderson Darren W, Lau Emily S, Morris Michele, Semenov Yevgeniy R, Triant Virginia A, Visweswaran Shyam, Strasser Zachary H, Klann Jeffrey G, Murphy Shawn N, Estiri Hossein
Abstract excerpt
BACKGROUND: Scalable identification of patients with post-acute sequelae of COVID-19 (PASC) is challenging due to a lack of reproducible precision phenotyping algorithms, which has led to suboptimal accuracy, demographic biases, and underestimation of the PASC. METHODS: In a retrospective case-control study, we developed a precision phenotyping algorithm for identifying cohorts of patients with PASC. We used...
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