[Thyroid cancer in a child with Cowden syndrome].

Abstract excerpt

Cowden disease (Cowden syndrome) refers to PTEN-associated hamartoma tumor syndromes. It arises due to a mutation in the phosphatase and tensin homolog gene, one of the main functions of which is cell cycle regulation. The presence of a mutation in the gene leads to uncontrolled cell growth, and patients have a lifelong increased risk of neoplasms of various degrees of malignancy. This article presents a clinical...

Topics

Join the communities discussing this publication.

• Child
• PTEN gene
• Hamartoma Syndrome, Multiple
• Mutation
• PTEN Phosphohydrolase