Article
B-cell and plasma cell activation in a mouse model of chronic muscle pain
1 Jul 2024
Abstract excerpt
• Adaptive neuroimmune interactions are implicated in chronic muscle pain and fibromyalgia pathology. • We used a repeated low pH insult rodent paradigm to model chronic widespread pain and assess B-cell activation and differentiation. • We have demonstrated mechanisms implicated in neuroimmune “crosstalk” between adaptive immune cells during chronic muscle pain. Fibromyalgia (FM) is a complex chronic...
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