Article
Efficacy and safety of tyrosine kinase inhibitors with thoracic radiotherapy for patients with oncogene-mutated non-small cell lung cancer: a meta-analysis.
Radiation oncology (London, England) - 6 Nov 2024
Li Wenxia, Wu Peiye, Liang Zhanpeng, Li Luzhen, Chen Yunqi, Zhang Wenjing, Zhang Huatang, Fang Cantu
Abstract excerpt
BACKGROUND: Tyrosine Kinase Inhibitors (TKIs) is an important therapy for patients with oncogene-mutated Non-Small Cell Lung Cancer (NSCLC). However, acquired resistance remains a major challenge. The efficacy of TKIs plus thoracic radiotherapy (RT) in oncogene-mutated NSCLC patients is uncertain. Therefore, we performed a meta-analysis to comprehensively evaluate the efficacy and safety of thoracic RT plus TKIs...
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