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Article

The study of Alzheimer's disease risk diagnosis based on natural killer cell marker genes in the multi-omics data.

Journal of Alzheimer's disease : JAD - 1 Nov 2025

Chen Xiaorong, Hu Fuyan, Chi Qingjia, Rao Congjun

Abstract excerpt

BackgroundAlzheimer's disease (AD) is a common neurodegenerative disorder, currently lacking effective early diagnostic methods. However, natural killer (NK) cells may play a potential role in AD pathogenesis.ObjectiveThis study aims to identify AD-related feature genes from NK cell markers to construct a diagnostic model and explore their potential biological mechanisms in AD.MethodsSingle-cell RNA sequencing...

Read the complete abstract on PubMed

Topics

Humans
Alzheimer Disease
Killer Cells, Natural
Biomarkers
Polymorphism, Single Nucleotide
Gene Regulatory Networks

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Algorithms

Multiomics

Source

Identifiers

PMID: 39497294
DOI: 10.1177/13872877241295316

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