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Article

Immune cell infiltration and drug sensitivity in PIK3CA-mutated esophageal squamous cell carcinoma: A TCGA database analysis.

Human immunology - 1 Nov 2024

He Shuo, Liu Qing, Luo Shujuan, Cai Bangwu, Chen Jiao, Peng Tianyuan, Wang Wei, Liu Tao, Lu Xiaomei, Zheng Shutao

Abstract excerpt

Recent studies have increasingly focused on PIK3CA mutations in esophageal squamous cell carcinoma (ESCC); however, the clinicopathological significance of these mutations within the tumor microenvironment remains underexplored. This study aimed to evaluate and compare the clinicopathological significance of mutated PIK3CA in ESCC using in silico analyses of the ESCC dataset from the TCGA database. We assessed...

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Share to Class I Phosphatidylinositol 3-Kinases
Share to Databases, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Neoplasm

Share to Esophageal Neoplasms

Share to Esophageal Squamous Cell Carcinoma

Share to Lymphocytes, Tumor-Infiltrating

Share to p38 Mitogen-Activated Protein Kinases

Share to Tumor Microenvironment

Source

Identifiers

PMID: 39490157
DOI: 10.1016/j.humimm.2024.111167

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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