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Causal relationship between bladder cancer and gut microbiota contributes to the gut-bladder axis: A two-sample Mendelian randomization study

2 Nov 2024

Abstract excerpt

• Five gut microbiota were found to be causally associated with bladder cancer. • Among these taxa, the genus Bilophila was identified as having a promoting effect on bladder cancer. • Sensitivity analyses did not reveal significant heterogeneity or horizontal pleiotropy among the included instrumental variables. • The gut microbiota taxa Enterobacteriaceae, Oscillibacter, Ruminococcaceae NK4A214 group, and...

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PMID: 39489648
DOI: 10.1016/j.urolonc.2024.10.014

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