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Assessing the causal relationship between gut microbiota and diabetic nephropathy: insights from two-sample Mendelian randomization

18 Mar 2024

Abstract excerpt

Background: The causal association between gut microbiota (GM) and the development of diabetic nephropathy (DN) remains uncertain. We sought to explore this potential association using two-sample Mendelian randomization (MR) analysis. Methods: Genome-wide association study (GWAS) data for GM were obtained from the MiBioGen consortium. GWAS data for DN and related phenotypes were collected from the FinngenR9 and...

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PMID: 38562415
DOI: 10.3389/fendo.2024.1329954

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