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A comprehensive investigation of Glycoprotein-based nucleic acid vaccines for Hantaan Virus

23 Oct 2024

Abstract excerpt

Hemorrhagic fever with renal syndrome (HFRS) occurs throughout Eurasia with considerable morbidity and mortality. Currently, the absence of specific treatments or effective antiviral drugs for hantavirus infection makes developing safe and effective vaccines a high priority. Here, we report the development of three novel nucleic acid vaccine candidates, mRNA, naked DNA, and DNA encapsulated in lipid...

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PMID: 39443512
DOI: 10.1038/s41541-024-00991-0

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