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Calorie restriction during gestation impacts maternal and offspring fecal microbiome in mice

4 Oct 2024

Abstract excerpt

Background Maternal undernutrition is the most common cause of fetal growth restriction (FGR) worldwide. FGR increases morbidity and mortality during infancy, as well as contributes to adult-onset diseases including obesity and type 2 diabetes. The role of the maternal or offspring microbiome in growth outcomes following FGR is not well understood. Methods FGR was induced by 30% maternal calorie restriction (CR)...

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PMID: 39429739
DOI: 10.3389/fendo.2024.1423464

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