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One-Hour Postload Glucose Is a More Sensitive Marker of Impaired β-Cell Function Than Two-Hour Postload Glucose

17 Oct 2024

Abstract excerpt

There is evidence that 1-h plasma glucose (PG) concentration during the 75-g oral glucose tolerance test (OGTT) is superior to 2-h PG level in predicting diabetes. We investigated the characteristics of insulin sensitivity and β-cell function behind this observation. After age, sex, and BMI matching, 496 study participants selected from 3,965 individuals without diabetes who were at high risk of type 2 diabetes...

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PMID: 39418325
DOI: 10.2337/db24-0652

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