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Combined Exposure to Folate and Lead during Pregnancy and Autistic-Like Behaviors among Canadian Children from the MIREC Pregnancy and Birth Cohort.

Environmental health perspectives - 1 Oct 2024

Alampi Joshua D, Lanphear Bruce P, MacFarlane Amanda J, Oulhote Youssef, Braun Joseph M, Muckle Gina, Arbuckle Tye E, Ashley-Martin Jillian, Hu Janice M Y, Chen Aimin, McCandless Lawrence C

Abstract excerpt

BACKGROUND: Folic acid (FA) supplementation may attenuate the associations between gestational exposure to certain chemicals and autism or autistic-like behaviors, but to our knowledge, this has not been assessed for lead. OBJECTIVES: We examined whether the relationship between gestational blood-lead levels (BLLs) and autistic-like behaviors was modified by gestational plasma total folate concentrations, FA...

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Identifiers

PMID: 39412272
DOI: 10.1289/EHP14479
PMCID: PMC11481933

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