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Article

Mendelian randomization suggests causal correlations between inflammatory cytokines and immune cells with mastitis.

Frontiers in immunology - 1 Jan 2024

Chen Jiaying, Su Ben, Zhang Xinyue, Gao Chao, Ji Yajie, Xue Xiaohong

Abstract excerpt

Objectives: Previous studies have reported that immunoinflammatory responses have associations with mastitis. Here, we aimed to further figure out whether circulating inflammatory cytokines and immune cells causally impact mastitis liability. Methods: The two-sample Mendelian randomization made use of genetic variances of 91 inflammatory cytokines from a large publicly available genome-wide association study...

Topics

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Cytokines
Genetic Predisposition to Disease
Genome-Wide Association Study
Immunophenotyping
Mastitis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mendelian Randomization Analysis

Polymorphism, Single Nucleotide

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Identifiers

PMID: 39399489
DOI: 10.3389/fimmu.2024.1409545
PMCID: PMC11466835

Genes

CD28
CX3CL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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