Article
Complete response to encorafenib plus binimetinib in a BRAF V600E-mutant metastasic malignant glomus tumor.
Oncotarget - 11 Oct 2024
Arregui Marta, Calles Antonio, Galera María Del Mar, Gutiérrez Ana, López-Jiménez Carlos, Agra Carolina, Fernández Adriana, Gutiérrez Natalia, Toro María de, Álvarez Rosa
Abstract excerpt
Glomus tumors (GT) are very rare mesenchymal neoplasms arising from glomus bodies, arteriovenous structures located in the dermis and involved in thermoregulation. Although most are benign, they may occasionally present malignant histological features associated with aggressive clinical behavior, metastatic spread, and poor response to conventional chemotherapy. The BRAF V600E mutation has been identified in a...
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