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Assessing different next-generation sequencing technologies for wastewater-based epidemiology

19 Sept 2024

Abstract excerpt

• Reliable SARS-CoV-2 wastewater surveillance is doable with various NGS technologies. • Sequencing error rates were lowest using novel Element Aviti sequencing. • Nanopore-based variant abundance estimates show good correlation with Aviti data. • Reducing ONT flow cell runtime to 5 h does not affect variant abundance estimates. Wastewater-based epidemiology has proven to be an important public health asset...

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PMID: 39388978
DOI: 10.1016/j.watres.2024.122465

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