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Article

Casual effects of type 1 diabetes mellitus on site-specific digestive cancers: a Mendelian randomisation analysis.

Frontiers in endocrinology - 1 Jan 2024

Zhao Jinli, Li Wenjin, Chen Libo, Li Mingyong, Deng Weiming

Abstract excerpt

Objective: Despite several observational studies attempting to investigate the potential association between type 1 diabetes mellitus (T1DM) and the risk of digestive cancers, the results remain controversial. The purpose of this study is to examine whether there is a causal relationship between T1DM and the risk of digestive cancers. Methods: We conducted a Mendelian randomisation (MR) study to systematically...

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Diabetes Mellitus, Type 1
Digestive System Neoplasms
Genetic Predisposition to Disease
Genome-Wide Association Study
Mendelian Randomization Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

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Identifiers

PMID: 39301314
DOI: 10.3389/fendo.2024.1407329
PMCID: PMC11410686

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