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Article

Association Study of CACNA1D, KCNJ11, KCNQ1, and CACNA1E Single-Nucleotide Polymorphisms with Type 2 Diabetes Mellitus.

International journal of molecular sciences - 24 Aug 2024

Díaz-García Juan Daniel, Leyva-Leyva Margarita, Sánchez-Aguillón Fabiola, de León-Bautista Mercedes Piedad, Fuentes-Venegas Abel, Torres-Viloria Alfredo, Tenorio-Aguirre Erika Karina, Morales-Lázaro Sara Luz, Olivo-Díaz Angélica, González-Ramírez Ricardo

Abstract excerpt

Type 2 diabetes mellitus (T2DM) is a complex chronic disease characterized by decreased insulin secretion and the development of insulin resistance. Previous genome-wide association studies demonstrated that single-nucleotide polymorphisms (SNPs) present in genes coding for ion channels involved in insulin secretion increase the risk of developing this disease. We determined the association of 16 SNPs found in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39273144
DOI: 10.3390/ijms25179196
PMCID: PMC11395491

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