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Regulatory Mechanism of Autophagy in Premature Ovarian Failure

10 Sept 2024

Abstract excerpt

Premature ovarian failure (POF) is intricately linked to cellular fates such as senescence, apoptosis, and impaired granulosa cell (GC) differentiation, each of which contributes to ovarian dysfunction and follicular depletion. Autophagy is essential in preventing POF by maintaining cellular homeostasis through the degradation and recycling of damaged organelles and proteins, thereby preserving ovarian function...

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PMID: 39256962
DOI: 10.1002/cbf.4122

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