Undulating Free Energy Landscapes Buffer Redox Chains from Environmental Fluctuations.

Abstract excerpt

Roller-coaster or undulating free energy landscapes, with alternating high and low potential cofactors, occur frequently in biological redox chains. Yet, there is little understanding of the possible advantages created by these landscapes. We examined the tetraheme subunit associated with Blastochloris viridis reaction centers, comparing the dynamics of the native protein and of hypothetical (in silico) mutants....

Topics

• Oxidation-Reduction
• Thermodynamics
• Electron Transport
• Mutation
• Photosynthetic Reaction Center Complex Proteins