Article
FABP4 facilitates epithelial-mesenchymal transition via elevating CD36 expression in glioma cells
6 Sept 2024
Abstract excerpt
• We determine the elevated FABP4 expression in glioblastoma with tissue samples and public databases including TCGA and CGGA. • Our results revealed the critical role of FABP4 in EMT process. • We delineated the FABP4-CD36 signaling pathway in glioma EMT. • FABP4-induced CD36 expression primarily activated non-canonical TGFβ signaling. Glioblastoma multiforme (GBM) is the most aggressive brain tumor with poor...
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