Article
Population genomics of Streptococcus mitis in UK and Ireland bloodstream infection and infective endocarditis cases.
Nature communications - 6 Sept 2024
Kalizang'oma Akuzike, Richard Damien, Kwambana-Adams Brenda, Coelho Juliana, Broughton Karen, Pichon Bruno, Hopkins Katie L, Chalker Victoria, Beleza Sandra, Bentley Stephen D, Chaguza Chrispin, Heyderman Robert S
Abstract excerpt
Streptococcus mitis is a leading cause of infective endocarditis (IE). However, our understanding of the genomic epidemiology and pathogenicity of IE-associated S. mitis is hampered by low IE incidence. Here we use whole genome sequencing of 129 S. mitis bloodstream infection (BSI) isolates collected between 2001-2016 from clinically diagnosed IE cases in the UK to investigate genetic diversity, antimicrobial...
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