Article
Inflammatory cytokine expression in Fabry disease: impact of disease phenotype and alterations under enzyme replacement therapy.
Frontiers in immunology - 1 Jan 2024
Yuan Yujing, Zhao Yawen, Li Fan, Ling Chen, Wu Yuan, Ma Wei, Wang Zhaoxia, Yuan Yun, Hao Hongjun, Zhang Wei
Abstract excerpt
Objectives: The aim of this study is to explore the expression of inflammatory cytokines (ICs) in Fabry disease (FD), the correlation between ICs and FD phenotypes, and the impact of enzyme replacement therapy (ERT) on IC expression. Methods: We recruited 67 FD patients and 44 healthy controls (HCs) and detected concentrations of the following ICs: interferon-γ, interleukin (IL)-1β, IL-2, IL-4, IL-5, IL-6, IL-8,...
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