Article
Scalable CNN-based classification of selective sweeps using derived allele frequencies.
Bioinformatics (Oxford, England) - 1 Sept 2024
van den Belt Sjoerd, Zhao Hanqing, Alachiotis Nikolaos
Abstract excerpt
MOTIVATION: Selective sweeps can successfully be distinguished from neutral genetic data using summary statistics and likelihood-based methods that analyze single nucleotide polymorphisms (SNPs). However, these methods are sensitive to confounding factors, such as severe population bottlenecks and old migration. By virtue of machine learning, and specifically convolutional neural networks (CNNs), new accurate...
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