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Article

A real world analysis of secondary BRAF variations after targeted therapy resistance in driver gene positive NSCLC.

Scientific reports - 1 Sept 2024

Liu DuJiang, Ding KaiBo, Yin KaiLai, Peng ZhongSheng, Li Xinyue, Pan Yang, Jin XuanHong, Xu YanJun

Abstract excerpt

Secondary BRAF variations have been identified as a mechanism of resistance to tyrosine kinase inhibitors (TKIs) in patients with driver gene-positive NSCLC. Nevertheless, there is still a lack of consensus regarding the characteristics and subsequent treatment strategies for these patients. We retrospectively reviewed the medical records of patients with driver gene-positive NSCLC who received TKIs therapy at...

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Source

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Identifiers

PMID: 39218919
DOI: 10.1038/s41598-024-71143-6
PMCID: PMC11366755

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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