Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expanded CD8 + CD38 + T Cell Population in Patients With Systemic Lupus Erythematosus Is Linked to Increased Infection Rates: A Prospective Study

30 Aug 2024

Abstract excerpt

Objective One of the leading causes of morbidity and mortality among patients with systemic lupus erythematosus (SLE) is infections. The expression of the ectonucleotidase CD38 on the surface of CD8+ T cells has been linked to compromised cytotoxic function. The aim of this prospective study was to assess whether the presence of CD8+CD38+ in the peripheral blood of patients with SLE can serve as a biomarker for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immune Cell Function and Interaction
Share to Systemic Lupus Erythematosus Research
Share to T-cell and B-cell Immunology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39212168
DOI: 10.1002/acr2.11725

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expanded CD8 + CD38 + T Cell Population in Patients With Systemic Lupus Erythematosus Is Linked to Increased Infection Rates: A Prospective StudyPMID 39212168Read ↗

Increased CD38 expression in T cells and circulating anti-CD38 IgG autoantibodies differentially correlate with distinct cytokine profiles and disease activity in systemic lupus erythematosus patients.Semantic proximity Read ↗

Systemic lupus erythematosus and infections.Semantic proximity Read ↗

Targeting CD38 Across Autoimmune and Plasma Cell–Driven Immune-Mediated Diseases: Rationale, Clinical Evidence, and Emerging Therapeutic LandscapeSemantic proximity Read ↗

Gene profiling of Epstein-Barr Virus and human endogenous retrovirus in peripheral blood mononuclear cells of SLE patients: immune response implicationsSemantic proximity Read ↗

Differential Gene Profiling of Epstein-Barr Virus and Human Endogenous Retrovirus in Peripheral Blood Mononuclear Cells of Patients with Systemic Lupus Erythematosus: Implications for Immune ResponseSemantic proximity Read ↗

Roles of CD38 in the Immune Response to Infection.Semantic proximity Read ↗

Identification and immunoassay of biomarkers associated with T cell exhaustion in systemic lupus erythematosusSemantic proximity Read ↗

Effector T-cells are expanded in systemic lupus erythematosus patients with high disease activity and damage indexes.Semantic proximity Read ↗

The reduced frequency of CD39+CD73+ B cell subsets in SLE patients is correlated with disease activitySemantic proximity Read ↗

Different Immunologic Profiles Are Associated With Distinct Clinical Phenotypes in Longitudinally Observed Patients With Systemic Lupus Erythematosus.Semantic proximity Read ↗

The proliferative activity levels of each immune cell population evaluated by mass cytometry are linked to the clinical phenotypes of systemic lupus erythematosus.Semantic proximity Read ↗

Aberrant phenotypes of circulating γδ-T cells may be involved in the onset of systemic lupus erythematosus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.