Article
Multiview representation learning for identification of novel cancer genes and their causative biological mechanisms.
Briefings in bioinformatics - 25 Jul 2024
Yang Jianye, Fu Haitao, Xue Feiyang, Li Menglu, Wu Yuyang, Yu Zhanhui, Luo Haohui, Gong Jing, Niu Xiaohui, Zhang Wen
Abstract excerpt
Tumorigenesis arises from the dysfunction of cancer genes, leading to uncontrolled cell proliferation through various mechanisms. Establishing a complete cancer gene catalogue will make precision oncology possible. Although existing methods based on graph neural networks (GNN) are effective in identifying cancer genes, they fall short in effectively integrating data from multiple views and interpreting predictive...
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