Article
Comprehensive liquid biopsy analysis for monitoring NSCLC patients under second-line osimertinib treatment
21 Oct 2024
Abstract excerpt
Background The heterogeneous and complex genetic landscape of NSCLC impacts the clinical outcomes of patients who will eventually develop resistance to osimertinib. Liquid biopsy (LB) analysis as a minimally invasive approach is a key step to efficiently identify resistance mechanisms and adjust to proper subsequent treatments. Materials and methods In the present study, we combined plasma-cfDNA and CTC analysis...
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