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Gene Expression Profiles of AHNAK2, DCSTAMP, FN1, and TERT Correlate With Mutational Status and Recurrence in Papillary Thyroid Carcinoma.

Genes, chromosomes & cancer - 1 Aug 2024

Staubitz-Vernazza Julia I, Müller Celine, Heymans Antonia, Nedwed Annekathrin Silvia, Schindeldecker Mario, Hartmann Monika, Kloth Michael, Schad Arno, Roth Wilfried, Musholt Thomas J, Hartmann Nils

Abstract excerpt

Papillary thyroid carcinoma (PTC), the most common malignancy of follicular cell derivation, is generally associated with good prognosis. Nevertheless, it is important to identify patients with aggressive PTCs and unfavorable outcome. Molecular markers such as BRAFV600E mutation and TERT promoter mutations have been proposed for risk stratification. While TERT promoter mutations have been frequently associated...

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Identifiers

PMID: 39193983
DOI: 10.1002/gcc.23256

Genes

TERT
DCSTAMP
FN1
AHNAK2

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Gene Expression Profiles of AHNAK2, DCSTAMP, FN1, and TERT Correlate With Mutational Status and Recurrence in Papillary Thyroid Carcinoma.PMID 39193983Read ↗

TERT mRNA Expression as a Novel Prognostic Marker in Papillary Thyroid CarcinomasSemantic proximity Read ↗

Prospective Analysis of TERT Promoter Mutations in Papillary Thyroid Carcinoma at a Single InstitutionSemantic proximity Read ↗

Preoperative Co-Mutation of BRAFV600E and TERT Promoter Predicts Tumor Aggressiveness and Recurrence-Free Survival in Papillary Thyroid Carcinoma.Semantic proximity Read ↗

Association of BRAF or TERT Promoter Mutations and Advanced Papillary Thyroid Carcinoma.Semantic proximity Read ↗

Risk stratification by combining common genetic mutations and TERT promoter methylation in papillary thyroid cancer.Semantic proximity Read ↗

TERT promoter Mutation and Its Association with Clinicopathological Features and Prognosis of Papillary Thyroid Cancer: A Meta-analysis.Semantic proximity Read ↗

Interaction of BRAF-induced ETS factors with mutant TERT promoter in papillary thyroid cancerSemantic proximity Read ↗

Impact of BRAF V600E and TERT Promoter Mutations on Response to Therapy in Papillary Thyroid CancerSemantic proximity Read ↗

Interplay of BRAF and TERT promoter mutations and Ki67 proliferation index in papillary thyroid carcinoma in Central Asians.Semantic proximity Read ↗

Genetic alterations and allele frequency of BRAF V600E and TERT mutation in papillary thyroid carcinoma with intermediate-to-high recurrence risk: a retrospective study.Semantic proximity Read ↗

TERT Promoter and BRAF V600E Mutations in Papillary Thyroid Cancer: A Single-Institution Experience in KoreaSemantic proximity Read ↗

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