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Article

Unraveling the impact of irritability on esophageal diseases: Insights from multivariable Mendelian randomization analysis.

Journal of affective disorders - 1 Dec 2024

Fang Pinhao, Zhou Jianfeng, Liang Zhiwen, Yang Yushang, Luan Siyuan, Xiao Xin, Li Xiaokun, Shang Qixin, Zhang Hanlu, Zeng Xiaoxi, Yuan Yong

Abstract excerpt

BACKGROUND: Previous studies have suggested a potential association between irritability and the risk of various diseases. However, establishing a causal relationship has remained a significant challenge. To address this issue, we employed Mendelian randomization (MR), a sophisticated approach that leverages genotype data to emulate the conditions of randomized controlled trials. This method enables us to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39187201
DOI: 10.1016/j.jad.2024.08.158

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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