Article
Acute kidney injury, an underrecognized feature of VEXAS syndrome.
Rheumatology (Oxford, England) - 1 Apr 2025
Kalantari Kambiz, Sullivan Megan M, Herrera Hernandez Loren P, Bu Lihong, Cornell Lynn D, Nasr Samih H, Fervenza Fernando C, Montes Daniel, Mangaonkar Abhishek A, Go Ronald S, Kusne Yael N, Patnaik Mrinal M, Lasho Terra L, Olteanu Horatiu, Reichard Kaaren K, Warrington Kenneth J, Koster Matthew J
Abstract excerpt
OBJECTIVES: Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic (VEXAS) syndrome is an autoinflammatory disease caused by somatic mutation of UBA1 and affects multiple organ systems. Involvement of the kidneys is not well characterized. We aimed to investigate the incidence, risk factors and histopathologic features of acute kidney injury (AKI) in VEXAS syndrome. METHODS: Patients with genetically confirmed...
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