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Article

Integration of multiomics features for blood-based early detection of colorectal cancer.

Molecular cancer - 22 Aug 2024

Gao Yibo, Cao Dandan, Li Mengfan, Zhao Fuqiang, Wang Pei, Mei Shiwen, Song Qianqian, Wang Pei, Nie Yanli, Zhao Wei, Wang Sizhen, Yan Hai, Wang Xishan, Jiao Yuchen, Liu Qian

Abstract excerpt

BACKGROUND: Early detection of colorectal cancer (CRC) significantly enhances patient outcomes. Conventional CRC screening tools, like endoscopy and stool-based tests, have constraints due to their invasiveness or suboptimal patient adherence. Recently, liquid biopsy employing plasma cell-free DNA (cfDNA) has emerged as a potential noninvasive screening technique for various malignancies. METHODS: In this...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39175001
DOI: 10.1186/s12943-024-01959-3
PMCID: PMC11340186

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